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Culture Positive Infectious Endophthalmitis Associated with Intravitreal Injection Treated at the Bascom Palmer Eye Institute: A 9-year Study

Culture Positive Infectious Endophthalmitis Associated with Intravitreal Injection Treated at the Bascom Palmer Eye Institute: A 9-year Study ABSTRACT Purpose: To report the clinical features, medications utilized, causative organisms, and visual acuity (VA) outcomes in patients with intravitreal injection associated endophthalmitis over the past decade. Design: Retrospective case series. Methods: Clinical and microbiology records were...

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Intraoperative Microscope-integrated Optical Coherence Tomography for Subretinal Gene Therapy Delivery

Intraoperative Microscope-integrated Optical Coherence Tomography for Subretinal Gene Therapy Delivery ABSTRACT Purpose: To report the novel use of microscope-integrated optical coherence tomography (MIOCT) as an adjunct to delivery of subretinal gene therapy. Setting: The Bascom Palmer Eye Institute, Miami, FL, USA Methods: The MIOCT was used intraoperatively during subretinal injections of adeno-associated viral serotype 2 vector...

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Long-term Outcomes of Human Embryonic Stem Cell Derived Retinal Pigment Epithelial Cell Transplantation for Retinal Degeneration from Two Phase I/II Trials

Long-term Outcomes of Human Embryonic Stem Cell Derived Retinal Pigment Epithelial Cell Transplantation for Retinal Degeneration from Two Phase I/II Trials ABSTRACT Purpose: To summarize long-term safety data and clinical outcomes of two prospective phase I/II studies assessing safety and tolerability of human Embryonic Stem Cell (hESC) derived retinal pigment epithelial (MA09-hRPE) cell transplantation in patients with atrophic...

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