Stem Cell Therapy for Retinal Disorders: Generation of Human RPE from Skin Biopsies of AMD Patients ABSTRACT Purpose: Retinal pigmented epithelium (RPE) derived from human induced pluripotent stem (iPS) cells is a promising source of cells for the replacement of degenerated RPE in patients with age-related macular degeneration (AMD), as use of patient-specific iPS will avoid the issue of graft rejection. Here we demonstrate that iPS can...

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