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Three-Dimensional Analysis of the Morphological Changes and Visual Outcomes in Neovascular Age-Related Macular Degeneration

ABSTRACT Purpose: To investigate the association of 3-D quantified lesions with best-corrected visual acuity (BCVA) in AMD. Methods: We retrospectively analyzed 65 eyes of 61 typical nAMD patients. Lesions at baseline and month 12 were manually delineated in OCT. Volumes of intraretinal fluid (IRF), subretinal fluid (SRF), subretinal hyperreflective material (SHRM), and pigment epithelial detachment (PED) were measured. Results: At...

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Choroidal Thickening and Hyperpermeability Related to Choroidal Ischemia

ABSTRACT Purpose: Choroidal hyperpermeability was first described as a characteristic indocyanine green angiography (ICGA) finding seen in eyes with central serous chorioretinopathy and has been regarded as closely related to the pathophysiology of this entity. In the present study, the role of choroidal ischemia in producing ICGA choroidal hyperpermeability has been investigated in patients with hypertensive choroidopathy related to...

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