Purpose: We present two different surgical approaches to address submacular hemorrhage. Setting / Venue: Department of Ophthalmology – Centro Hospitalar e Universitário de Coimbra, Portugal. Methods: We present the cases of two patients with submacular hemorrhage that underwent 23-gauge pars plana vitrectomy (PPV) assisted by tissue plasminogen activator (t-PA) The first case refers to a 59 year-old woman, with high myopia who...

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