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Biomarkers and Predictors for Functional and Anatomic Outcomes for Pars Plana Vitrectomy and Peeling of the Internal Limiting Membrane in Naïve Diabetic Macular Edema. The VITAL Study

ABSTRACT Aim: To evaluate the role of small gauge PPV as a first line treatment for naïve DME with a follow-up of 24 months and to investigate biomarkers and predictive factors for visual and anatomical outcome. Patients & Method: One hundred and twenty eyes, from 120 patients with a mean age of 67.0±14.9 years, were evaluated. Results: The mean baseline BCVA was 0.66 ± 0.14 logMAR, improved to 0.52 ± 0.21 logMAR after 12...

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Treatment of Diabetic Macular Edema in Anti-VEGF Nonresponders. Long Time Real Life Results

ABSTRACT Purpose: In the retrospective single center study, we evaluated the effectiveness of Dexamethasone implant (DEX) and fluocinolone acetonide (FAc) implant in patients with diabetic macular edema (DME) who insufficiently responded to anti-VEGF therapy. Methods: In total 30 eyes without improvement of best corrected visual acuity (BCVA) and central foveal thickness (CFT) after treatment with 3-14 anti-VEGF injections (ranibizumab...

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