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Modeling of Silicone Oil Emulsification Under Posterior Retinal Tamponade

Andrii Serhiienko, Viktoriia Serhiienko, Konstantin Tkachuk, Ukraine To simulate the interaction of silicone oil and intraocular fluids, we used the emulsions of balanced saline and silicone oil (SO-BSS) of different concentrations (10.0%, 20.0%, 33.3%, 50%, and 66.7%) and samples taken from 23 patients after a surgery for rheumatogenic retinal detachment. The pycnometer method was used for evaluation of density of physico-chemical models,...

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Changes of Physico-chemical Properties of Silicone Oil Associated with a Retinal Detachment

ABSTRACT The source material for our study was 23 samples of silicone oil, aspirated from the vitreous cavities of the eyes of patients after a tamponade about the rheumatogenic and traction retinal detachment. The average life of silicone oil in the eye was 3.5 months. In all cases, a 1300 cSt – viscosity Oxane silicone oil, Baush + Lomb, the UK, was used for tamponade. All samples were stabilized, resulting in colloidal systems...

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Analysis of Amount and Density of Residual Silicone Oil Fragments in Vitreous Cavity After Retinal Detachment Surgery

ABSTRACT Purpose: To analyze the amount of residual silicon oil (SO) fragments in vitreous cavity after retinal detachment surgery. Methods: Twenty-six patients (26 eyes) (mean age 47. years) underwent ultrasound examination after SO removal (Oxane SO 1300, Bousch&Lomb). The amount of hyperechogenic silicone oil fragments in vitreous cavity was analyzed in four quadrants of multiple scans using method of neural circuits. Results: In all...

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A Retrospective Study of Serial Endophthalmitis in Ukraine

A Retrospective Study of Serial Endophthalmitis in Ukraine ABSTRACT Purpose: To analyze rate, causes, therapeutic approaches and complications of serial endophthalmitis in Ukraine. Methods: A retrospective study of 4 episodes of serial endophthalmitis from 4 different clinics in the period of time from 1996 till 2016 was performed. The series consisted of 12, 22, 3 and 24 cases of postoperative endophthalmitis. Case series were studied...

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Standard IVI Technique as a Risk Factors for Postoperative Endophthalmitis: Vitreous Contamination Due to Injection of Cellular Content of Ocular Tissues Cut by the Needle Tip

Standard IVI Technique as a Risk Factors for Postoperative Endophthalmitis: Vitreous Contamination Due to Injection of Cellular Content of Ocular Tissues Cut by the Needle Tip ABSTRACT Purpose: Intravitreal injections (IVI) have associated risk of intraocular inflammation, and considered to be the main cause of intraocular septic and aseptic reaction. The mechanism of vitreous contamination is not studied well. Our purpose was to...

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Selective Laser Trabecuplasty in Treatment of Secondary Open Angle Silicone-induced Glaucoma

Selective Laser Trabecuplasty in Treatment of Secondary Open Angle Silicone-induced Glaucoma ABSTRACT Selective Laser Trabeculoplasty (SLT) proved to be safe and effective in patients with primary open angle glaucoma, pseudoexfoliation glaucoma, glaucoma secondary to pigment dispersion syndrome. Among factors determining a development a silicone-induced glaucoma the most reasoning seems an impact of silicone oil on anterior chamber angle...

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29 G Endoillumination Assisted Scleral Buckling Using New Illuminated Indenter-marker

The authors declare potential conflict of interest regarding the new design of the instrument. Purpose: To report a 29 gauge endoillumination assisted scleral buckling technique for rhegmatogenous retinal detachment (RRD) using a new illuminated indenter-marker and non-contact wide-angle viewing system. Methods: Nine consecutive cases with RRD underwent 29 gauge endoillumination assisted scleral buckling using a new instrument, illuminated...

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Effectiveness of Low-energy Light Irradiation for Exudative AMD After Anti-VEGF Therapy

Studied the effectiveness of low-energy light irradiation in patients with exudative form of age-related macular degeneration after anti-VEGF therapy. The main group included 62 patients (the 69 eyes), who received two courses of low-energy light radiation within 6 months after the anti-VEGF therapy. A control group of 41 patients (44 eyes) to the monitoring took place only anti-VEGF therapy. The total period of observation was 1 year....

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Intravitreal Levoxacin as Initial Treatment of Acute Exogenous Endophthalmitis Before PPV

The authors declare no conflict of interest. Purpose: To report the efficacy of intravitreal levofloxacin as an initial treatment of acute exogenous endophthalmitis on the stage of transportation of the patients to the vitreoretinal department and before early pars plana vitrectomy (PPV). Methods: Thirty patients (34 eyes) with exogenous endophthalmitis were included to this prospective non-randomized study. Fourteen patients (41.2%) had...

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Modification of Vitreoretinal Instruments: Perfection or Complication

Advantages: To reduce the disadvantages of standard vitreoretinal instruments (cannulas and ILM forceps) which arise during the use on eyes with long axial length. Methods: Two types of aspiration cannulas and one ILM forceps for surgery on eyes with long axial length were designed on schematic eye drawing and manufactured. Forty-four eyes with high-grade myopia (axial length 28-33.5 mm) were operated for retinal detachment and macular...

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Closer Look at Physical Properties of PFCL and Silicone Oil

Advantages: To study physical properties of perfluorocarbon liquids and silicone oil in vitro. Methods: Samples of perfluodecalin and silicone oil were taken to study their physical properties under microscope in dormant conditions. Samples of emulsified silicone oil were studied under microscope in BSS drop to evaluate physical properties in dormant conditions. Additional sample staining with the use of stain Sudan III was performed....

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Comparison of Endovitreal Triamcinolone with Betamethasone in DME

Advantages: Use of intravitreal injection of crystalline corticosteroids- bethamethasone and triamcinole dose of 4 mg in 0.1 ml allows to improve visual acuity and restore adequate morphological retinal thickness in patients with diffuse diabetic macular edema. Methods: Comparison of efficacy and safety of intravitreal injection of 4 mg (0.1 mL) triamcinolon (36 patients – 40 eyes) and 4 mg (0.1 mL) bethamethasone (60 patients...

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Effectiveness of Combined Betamethasone and Laser Coagulation for DME

Advantages: Combined treatment of diffuse diabetic macular edema using intravitreal injection of bethamethasone and laser coagulation is effective in improving visual acuity and restoration of the morphofunctional state of the retina. Methods: Intravitreal injection 4 mg (0.1 ml) of bethamethasone combined with laser coagulation was conducted in 33 patients (33 eyes) with diffused diabetic macular edema. Patients were divided into 2...

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Modified Vitreo Retinal Instruments for Macular Surgery on Eyes with High Myopia

Advantages: To improve certain vitreo-retinal instruments to enhance the accesses to posterior pole and avoid complications during macular surgery in highly myopic eyes. Methods: Modified double bent aspiration 23-gauge cannula with 30.00 mm working part was used during pars plana vitrectomy in highly myopic eyes. The aspiration of residual PFCL or BSS with modified cannula was performed under visual control using different kinds of...

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Correlation Between Post-operative OCT Changes and Best Corrected VA After PPV for RD

Advantages: To reveal post-operative specific changes of macular layers using OCT in patients with rhegmatogenous retinal detachment (RD) with macula-off and macula-on pre-op; to provide correlation between OCT changes and post-operative best corrected visual acuity (BCVA). Methods: In 42 patients with rhegmatogenous RD in 1 month after pars-plana vitrectomy OCT analysis (HD-OCT, Cirrus, Carl Zeiss, Meditec) was performed to detect...

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Determination of Ischemic Diabetic Maculopathy According to SOCT Data

Advantages: To develop the coefficient of ischemia in order to characterize pathological changes of retinal architectonics in microvascular occlusion in ischemic diabetic maculopathy according to non invasive method spectral optical coherence tomography in comparison to non ischemic retina without usage of fluorescent angiography. Methods: There were 25 eyes (18 patients) with diabetic macular ischemia to which along with general clinical...

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Unusual Post-op High VA After Scleral Buckling with Incomplete Macular Reattachment

Advantages: To report a clinical case of long-standing post-operative high best corrected visual acuity (BCVA) after scleral buckling procedure due to rhegmatogenous retinal detachment (RD) with incomplete macular reattachment. Methods: A sixty-four-year-old female was admitted to Kyiv Eye Microsurgery Center in September 2011 with diagnosis of rhegmatogenous RD (extension from 5 to 11 o’clock) on her right eye temporal side with...

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Variable Clinical Manifestations of Bilateral Rhegmatogenous Retinal Detachment

Diana Chichur, Andriy Sergienko (Kyiv, Ukraine) Advantages: This study reports different clinical types of rhegmatogenous retinal detachment (RRD) that require different surgical methods of repair. Methods: Retrospective review of 80 patients presenting with bilateral RRD. Effectiveness / Safety: Two types of bilateral RRD clinical course were distinguished from clinical assessment: type I with a more favorable outcome, (13.7% of the...

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Efficacy of a Modified Immunosuppressive Therapy Method in Patients Suffering from Rhegmatogenous Retinal Detachment

Diana Chichur, Andrej Sergienko (Kyiv, Ukraine) Advantages: The thesis is devoted to improving efficacy of treatment of rhegmatogenous retinal detachment (RRD) patients, aimed to prevent the disease relapse and its development in the fellow eye by using a modified immunosuppressive therapy method, by studying autoimmune process activity in patients with different disease course. Methods: 80 patients suffering from bilateral RRD were...

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Management of Closed Funnel Retinal Detachment with Giant Tears

Andriy Sergienko, Lyubomyr Lytvynchuk (Kyiv, Ukraine) Advantages: To achieve retinal reattachment in RD cases with contraction and shrinking of the retina. Methods: Five cases ware include into the study. The steps of surgical technique were following: 1. Lensectomy and bimanual removal of the anterior proliferative loop. 2. Stretching of retinal edges and creation of triangular entry into the RD funnel. Removal of accessible epiretinal...

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The Frequency of Silicone Oil Induced Glaucoma After Pars Plana Vitrectomy

A. Sergienko, L. Lytvynchuk, I. Kozlovska, Galina Y. Lavrenchuk, O. Fylypchuk, V. Siriachenko (Kyiv, Ukraine) Advantages: To evaluate the incidence of secondary glaucoma after pars plana vitrectomy due to silicon oil emulsification in different terms of endotamponade and to study the efficacy of trabeculectomy in refractory cases to medical treatment. Methods: Sixty-four (64) patients with different duration of silicon oil endotamponade...

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Biological Effects of Pharmacological Agents on Proliferative Cellular Activity in Vitro

Olena Vlasko, Andriy Sergienko, Lyubomyr Lytvynchuk, Galina Y. Lavrenchuk (Kyiv, Ukraine) Advantages: To study cellular effects of pharmacological agents (drugs, dyes and substitutes) on the highly proliferative fibroblast-like cell strain L929, as an in vitro model of proliferative vitreoretinopathy processes. Methods: Pharmacological agents for intravitreal administration (betamethasone, triamcynolone acetonide, mytomicine C,...

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Cellular Effects of Vitreous Body and Subretinal Fluid in Vitro

Andriy Sergienko, Luybomyr Lytvynchuk, Galina Lavrinchuk, Olena Vlasko (Kyiv, Ukraine) Objective: To evaluate the effects of vitreous and subretinal fluid on fibroblast-like cell strains, as a model of proliferative processes in vitro. To find out the evidences that PVR development is dependent not only on RPE migration. Methods: Eleven vitreous aspirates and 9 subretinal fluid samples, taken during PPV in eyes with retinal detachment,...

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Distribution of Microelements in Vitreous Body and Subretinal Fluid in the Eyes with Retinal Detachment

Andriy Sergienko, Olena Leus, Victoriia Siriachenko (Kyiv, Ukraine) Objective: To determine the trends of microelement distribution in vitreous and subretinal fluid in the eyes with retinal detachment. Methods: Semi-quantitative emission spectral analysis of 60 vitreous body aspirates and 36 subretinal fluid samples, taken during PPV in patients with retinal detachment, was performed. 10 cadaverous vitreous samples were used as controls....

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Long-Term Effects of Intravitreal Bevacizumab (Avastin) in the Treatment of Choroidal Neovascular Membranes Due to Pathologic Myopia

http://www.evrs.eu/medias/2010/congress/Non-Age-Related-Macular-Degeneration-Nor-Diabetes-Neovascularization.flv Andriy Sergienko, Lyubomyr Lytvynchuk (Kyiv, Ukraine) Advantages: Intravitreal bevacizumab (Avastin) is a new and safe surgical treatment for choroidal neovascularization due pathologic myopia (myopic CNV). It allows controlling CNV activity and does not lead to development of foveal chorioretinal atrophy. In some cases, it...

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Surgical Treatment of von Hippel Peripheral Capillary Hemangioma Complications

http://www.evrs.eu/medias/2010/congress/Vascular-Pathologies-in-Young-Patients.flv Andriy Sergiienko, Lyubomyr Lytvynchuk, Oleksandr Fillipchuk (Kiev, Ukraine) Advantages: Exudative maculopathy and tractional retinal detachment are common complication of peripheral capillary hemangioma. Surgical approach necessitates big challenges and careful treatment planning. Methods: 5 patients with exudative maculopathy and tractional retinal...

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What Can We Do to Improve and Increase the Efficacy of Our Service Delivered to the Patients?

Authors: Lyubomyr Lytvynchuk, Andrii M. Sergienko, Kiev, Ukraine Advantages: Taking care of themselves the surgeons save strength to deliver medical service to the patients. The accuracy of the hand and fingers movements is dependent on the physical status of the whole body. Methods: The idea is to make the surgeons pay attention to the self-posturing during the surgery and to increase their physical activity during the operating day. Some...

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Microelements in Eyes with Proliferative Diabetic, Traumatic Retinopathy and Detached Retina

Andriy Sergienko, MD (Kiev, Ukraine) PURPOSE: To evaluate role of microelements in development of proliferative retinopathy of different pathogenesis. METHODS: Seventy seven eyes with retinal detachment, 51eyes with proliferative diabetic retinopathy and 25 eyes traumatic retinopathy were included in this study. Thirty postmortem human eyes served as a control. Intraoperatively taken vitreous and subretinal fluid was used for the...

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Method of Safe Vitrectomy Technique

Andriy Sergienko, MD (Kiev, Ukraine), Alexander Filipchuk, MD (Kiev, Ukraine) PURPOSE: To evaluate efficacy of the method developed for safe vitrectomy manipulations. METHODS: A design of the developed instrument is supplied with thin irrigation tube which is fixed near a tip of the vitreo-cutter. The water jet from the tube allows to prevent capture of the retina and to control removal of vitreous. Initial trial of the instrument was...

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Acid-Base Balance of Eye Posterior Segment in Retinal Detachement with PVR

Andrij M.Sergienko*, E. Leus, D. Chichur. Eye Microsurgery Center, Kijv, Ukraine. Purpose: To evaluate the consequence of acidity intraocular fluids in pathogenesis of proliferative vitreoretinopathy. Methods: In a study 210 eyes with retinal detachment and PVR underwent operative treatment. In operative theatre subretinal fluid and vitreus body and blood taking up and measuring of pH were performed. Results: Diapason of consequence pH were...

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