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Intravitreal Decorin as an Adjuvant Therapy to Prevent Proliferative Vitreoretinopathy in Perforating Injuries: A Pilot Study

Intravitreal Decorin as an Adjuvant Therapy to Prevent Proliferative Vitreoretinopathy in Perforating Injuries: A Pilot Study ABSTRACT Purpose: To determine the safety, tolerability, and efficacy of human recombinant decorin protein, a transforming growth factor ß (TGFß) inhibitor in preventing proliferative vitreoretinopathy (PVR) in patients with perforating globe injuries. Methods: This is a prospective, single-center,...

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Combined Photodynamic Therapy and Intravitreal Triamcinolone Injection for the Treatment of Subfoveal Choroidal Neovascularization

Noha Khater, (Cairo, Egypt), Hoda, MH Mostafa, MD (Cairo, Egypt), Mahmoud Soliman (Cairo, Egypt), Tamer Macky, MD (Cairo, Egypt) PURPOSE: To evaluate the outcomes of combined intravitreal triamcinolone (IVTA) and photodynamic therapy (PDT) in the treatment of subfoveal choroidal neovascularization (CNV) caused by age related macular degeneration (AMD) and myopia. METHODS: Fifteen eyes from 15 patients with subfoveal CNV caused by AMD (n=10)...

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Retinal Toxicity to Triamcinolone Acetonide’s Vehicle: An Electrophysiology and Electromicroscopy Study

Tamer Macky, MD (Cairo, Egypt), Dina Helmy, MD (Cairo, Egypt), Nihal El Shazly, MD (Cairo, Egypt) PURPOSE: To assess rabbit retinal toxicity to triamcinolone acetonide vehicle, benzyl alcohol, when injected intravitreally. METHODS: This prospective comparative experimental study included 24 pigmented rabbits assigned into 2 groups; group 1 (experiment, n=12) received intravitreal 0.1ml of benzyl alcohol (BA), and group 2 (control, n=12)...

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Ultrasound Biomicroscopy of the Sclerotomy Sites Following Pars Plana Vitrectomy for Diabetic Eye Disease

Tamer Macky, MD (Cairo, Egypt), Pakinam H Fouad, MD (Cairo, Egypt), Mahmoud M. Soliman, MD (Cairo, Egypt), Nahla Sobhy, MSc (Cairo, Egypt) PURPOSE: This study was aimed at assessing changes at the sclerotomy site using the ultrasound biomicroscopy (UBM) in eyes that underwent pars plana vitrectomy for complications of proliferative diabetic retinopathy. METHODS: Twenty one eyes of 15 patients with vitreous hemorrhage and /or tractional...

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Visual Field Changes in Diabetic Patients: Frequency Doubling Perimetry versus Standard Automated Perimetry

Mahmoud M. Soliman, MD, Noha Khater, MD, FRCSEd, MRCOphth., Tamer A. Macky, MD, FRCSEd, Naglaa H. Ali, M.Sc Purpose: To compare visual field changes obtained by Frequency Doubling Perimetry (FDP) to those obtained by Standard Automated Perimetry (SAP) in diabetic patients. Setting: Department of Ophthalmology, Cairo University Hospitals, Cairo, Egypt. Methods: Twenty diabetic patients with no clinically visible diabetic retinal changes had...

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Bilateral Endogenous Candida Endophthalmitis Following Intravenous Catheterization in Diabetic Patients

Mahmoud M. Soliman, MD, Tamer A. Macky, MD, FRCSEd, Noha Khater, MD, FRCSEd, MRCOphth. Purpose: To report the clinical findings and treatment possibilities of diabetic patients with bilateral Endogenous Candida Endophthalmitis. Setting: Department of Ophthalmology, Cairo University Hospitals, Cairo, Egypt. Methods: Three diabetic patients presented to us with subacute bilateral diminution of vision. Their mean age was 63 years (ranging from...

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The Patency of Superior Ciliary Sulcus in Aphakic Silicon-Filled Eyes: an Ultrasound Biomicroscopy Study

Tamer A. Macky, MD, FRCSEd, Noha Khater, MD, FRCSEd, MRCOphth., Mahmoud M. Soliman, MD, Mohammed Nasr, M.Sc. Purpose: To assess the patency of the superior ciliary sulcus in aphakic silicon-filled eyes by Ultrasound Biomicroscopy (UBM). Setting: Department of Ophthalmology, Cairo University Hospitals, Cairo, Egypt. Patients and methods: Ten aphakic silicone-filled eyes of ten patients were evaluated using UBM. The UBM examination of the...

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Intravitreal Triamcinolone Acetonide for Diabetic Macular Edema Part II: Initial Intervention

Mahmoud M. Soliman, MD, Tamer A. Macky, MD, FRCSED, Nermeen A. Fawzi, M.Sc., Noha Khater, MD, FRCSED, MRCOphth. Purpose: To evaluate the clinical outcome and safety of intravitreal injection of triamcinolone acetonide (TA) as an initial therapy for diffuse diabetic macular edema. Setting: Department of Ophthalmology, Cairo University Hospitals, Cairo, Egypt. Methods: Ten eyes of eight patients with diffuse clinically significant macular...

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Intravitreal Triamcinolone Acetonide for Diabetic Macular Edema: Part I: Refractory Cases: Two Years Experience

Mahmoud M. Soliman, MD, Tamer A. Macky, MD, FRCSED, Nermeen A. Fawzi, M.Sc., Noha Khater, MD, FRCSED, MRCOphth. Purpose: To report our two-years experience with the safety and efficacy of intravitreal triamcinolone acetonide (TA) in treating diffuse diabetic macular edema refractory to laser. Setting: Department of Ophthalmology, Cairo University Hospitals, Cairo, Egypt. Methods: Fourteen eyes of 10 patients with clinically significant...

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Intravitreal Triamcinolone Acetonide During Phacoemulsification for Patients with Diabetic Macular Edema and Dense Cataracts

Noha Khater, MD, FRCSED, MRCOphth., Mahmoud M. Soliman, MD, Nermeen A. Fawzi, M. Sc., Tamer A. Macky, MD, FRCSED Purpose: To evaluate the efficacy of intravitreal triamcinolone acetonide (TA) during phacoemulsification in preventing deterioration of macular edema in diabetic patients with clinically significant cataract. Setting: Department of Ophthalmology, Cairo University Hospitals, Cairo, Egypt Methods: Twenty four eyes of eighteen...

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