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Treatment of Atrophic Macular Degeneration with Subthreshold High Density Micropulse Grid Laser Therapy

Stephen H. Sinclair, Jeffrey K. Luttrull, USA Background: Traditionally macular degeneration has been followed by physician examination, which fails to detect structural change, and has not been treated until the development of subretinal neovascularization. The results of treatment, however, have been extremely poor with little improvement in chart acuity, commonly utilized as the primary outcome, but a measure that has never been...

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Micropulse Contiguous Grid Laser for Diffuse DME

Objective: To investigate micropulse contiguous grid laser in fovea involved DDME and to correlate SD-OCT structural changes with resolution target visual fields. Purpose: To investigate micropulse contiguous grid laser in the treatment of eyes with DDME involving the fovea, and second, to correlate OCT findings with resolution target visual field (RTVF) measurements of threshold acuity at fixation, best acuity measured at any...

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Micropulse Contiguous Grid Laser for Diffuse DME

Objective: To investigate micropulse contiguous grid laser in fovea involved DDME and to correlate SD-OCT structural changes with resolution target visual fields. Purpose: To investigate micropulse contiguous grid laser in the treatment of eyes with DDME involving the fovea, and second, to correlate OCT findings with resolution target visual field (RTVF) measurements of threshold acuity at fixation, best acuity measured at any intercept...

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Intravitreal Procrit in Eyes with Geographic Atrophy Secondary to ARMD

Media not available due to technical recording problems. EVRS is very sorry for the inconvenience.   Purpose: To investigate the role of Procrit intravitreal injections in stabilizing vision and geographic atrophy (GA) in eyes with atrophic AMD and to characterize SD-OCT and central visual field acuity perimetry (Omnifield) findings associated with GA. Methods: A retrospective pilot study examined eyes treated off-label with Procrit...

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Micropulse Contiguous Grid Laser for Resistant Diffuse DME

Purpose: To investigate micropulse contiguous grid laser (MCGL) for DDME involving the fovea, and to correlate OCT findings with resolution target visual fields (RTVF) scotomas and global macular acuity (GMA). Methods: One year retrospective review of sequentially treated eyes including, OCT, FA, RTVF and NEI-VFQ 25. Results: In 56 eyes GMA improved 0.2 logMAR in 34%, with none worsening >0.3 logMAR. Central OCT decreased 173 µm+9.3....

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Micropulse Contiguous Grid Laser in Eyes with Diffuse Macular Edema Due to Diabetic Retinopathy

SH Sinclair (Drexel Univ School Med), B Parvus (Pennsylvania College of Osteopathic Medicine), L Lofdahl (Salus University), P Presti (Georgia Institute of Technology, Atlanta) Objective: To investigate micropulse contiguous grid laser in the treatment of eyes with diffuse diabetic macular edema (DDME) involving the fovea, resistant to prior treatment and second, to correlate OCT findings with central discriminant visual fields...

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Intravitreal Procrit in Eyes with Geographic Atrophy Secondary to ARMD

C Majcher (Salus), SH Sinclair (Drexel Univ School Med), W Li (Drexel Univ School Med), P Presti (Georgia Institute of Technology, Atlanta) Objective: Investigate erythropoietin intravitreal injections stabilization of central discriminant visual fields (CDVF) and GA progression in atrophic ARMD and correlate OCT findings with CDVF and patterns of GA progression. Methods: Retrospective pilot study of patients with GA AMD with fovea...

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Experience of Intravitreal Erythropoietin Therapy for Eyes with Chronic and Progressive Diabetic Macular Edema

http://www.evrs.eu/medias/2010/congress/Non-Proliferative-Diabetic-Maculopathies.flv Stephen H. Sinclair (Dept. of Ophthalmology, Drexel University College of Medicine, Philadelphia, PA, USA), 1, Weiye Li (Dept. of Ophthalmology, Drexel University College of Medicine, Philadelphia, PA, USA / Laboratory of Clinical Visual Sciences, Institute of Health Sciences (IHS), Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of...

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Interactive Computer Programs Improve Vision Testing for Ocular Screening, Treatment Evaluation and Post Treatment Surveillance

http://www.evrs.eu/medias/2008/congress/Interactive-Computer-Programs-Improve-Vision-Testing-for-Ocular-Screening,-Treatment-Evaluation-and-Post-Treatment-Surveillance.flv Stephen H. Sinclair, Yaprak Banu Unver, Gulderen Aktan Yavuz Advantages: Ophthalmologists overall have limited themselves in understanding and treatment of ocular disease because of the limited methods of traditional vision measurement that are physician dependent....

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Effect on High Contrast Discriminated Target Central Fields of Photodynamic Therapy with Vertporphyrin for CNVM Due to AMD

Stephen H. Sinclair, MD (Media, PA),* Weiye Li, MD (Media, PA), Peter Presti, (Media, PA)* PURPOSE: Vision outcomes for treatment of AMD CNVM have been previously evaluated using visual acuity with severe limitations. Central visual field testing with discriminated targets appears to offer significant advantages. METHODS: In this cohort, 31 eyes of 29 patients undergoing PDT with intravitreal triamcinolone for AMD CNVM underwent IVFA, BCVA...

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Graphic Blur Simulation of Vision Loss in Patients with Macular Disease Using Results of Discriminated Target Central Fields

Stephen H. Sinclair, MD Background: Images representing the vision of eyes with retinal disease have been presented in the past but with no verification of authenticity. Central visual fields of discriminated targets have allowed production of simulations using a blur paradigm to represent loss of resolution due to spherical blur, but these simulations have not been verified for macular disease. Patients and methods: For 22 patients with...

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