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Surgical Displacement of Medium-Sized Submacular Hemorrhage

http://www.evrs.eu/medias/2009/congress/Hemorrhages.flv Author: Sophie J. Bakri, Rochester, MN, USA Advantages: Surgical displacement of medium-sized thick submacular hemorrhage has the advantage of minimizing the toxic effects of blood on the retina. Methods: Pars plana vitrectomy, subretinal tPA and air-fluid exchange is performed. The patient lies flat on his back for 30 minutes, then upright for the next 24 hours. Effectiveness /...

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Vitrectomy Session – Silicone

http://www.evrs.eu/medias/2007/videos/vitrectomysession-silicone.flv

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Stability of Bevacizumab (Avastin) after Withdrawal into a Syringe and Refrigeration or Freezing

Colin A. McCannel, MD (Rochester, MN), Sophie J. Bakri, MD (Rochester, MN), Melissa R. Snyder, PhD (Rochester, MN), Jose S. Pulido, MD (Rochester, MN), Michael W. Stewart, MD (Jacksonville, FL), Frederick J. Troendle, PhD (Jacksonville, FL), William T. Weiss, (Rochester, MN), Ravinder J. Singh, PhD (Rochester, MN) PURPOSE: To assess the stability of bevacizumab (Avastin) over time after withdrawal into a syringe and refrigeration or...

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Pharmacokinetics of Intravitreal Bevacizumab (Avastin)

http://www.evrs.eu/medias/2006/congress/Pharmacokinetics-of-Intravitreal-Bevacizumab-(Avastin).swf Sophie J Bakri, MD (Cleveland, OH), Melissa Snyder, PhD (Rochester, MN), Jose S. Pulido, MD (Rochester, MN), Joel Reid, PhD (Rochester, MN), Ravinder Singh, PhD (Rochester, MN) PURPOSE: To describe the pharmacokinetics of 1.25 mg of intravitreal bevacizumab (avastin). METHODS: 1.25 mg (0.05cc) of bevacizumab was injected into the vitreous...

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Absence of Histologic Retinal Toxicity with Standard Clinical Doses of Intravitreal Bevacizumab in a Rabbit Model

Sophie J Bakri, MD (Cleveland, OH), J.D. Cameron, MD (Rochester, MN), Jose S. Pulido, MD (Rochester, MN), Colin A. McCannel, MD (Rochester, MN), Ronald Marler, DVM, PhD (Scottsdale, AZ) PURPOSE: To evaluate the retinal toxicity of intravitreal bevacizumab in an animal model. METHODS: Bevacizumab was injected into the vitreous of one eye of each of 8 Dutch-belted rabbits; the other eye served as a control. Four rabbits received a dose of...

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