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Intravitreal Decorin as an Adjuvant Therapy to Prevent Proliferative Vitreoretinopathy in Perforating Injuries: A Pilot Study

Intravitreal Decorin as an Adjuvant Therapy to Prevent Proliferative Vitreoretinopathy in Perforating Injuries: A Pilot Study ABSTRACT Purpose: To determine the safety, tolerability, and efficacy of human recombinant decorin protein, a transforming growth factor ß (TGFß) inhibitor in preventing proliferative vitreoretinopathy (PVR) in patients with perforating globe injuries. Methods: This is a prospective, single-center,...

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Expression of VEGF and PEDF in Choroidal Neovascular Membranes Following Verteporfin Photodynamic Therapy

Olcay Tatar, (Tuebingen, Germany), Annemarie Adam, (Tuebingen, Germany), Kei Shinoda, MD, PhD (Tokyo, Japan), Peter Stalmans, MD, PhD (Leuven, Belgium), Claus Eckardt, MD (Frankfurt, Germany), Matthias Lüke, MD (Tuebingen, Germany), Karl Ulrich Bartz-Schmidt (Tuebingen, Germany), Salvatore Grisanti, MD (Tuebingen, Germany) PURPOSE: To examine the impact of photodynamic therapy (PDT) on pigment epithelium derived factor (PEDF) expression...

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Expression of VEGF and Endostatin in Human Choroidal Neovascular Membranes Following Verteporfin Photodynamic Therapy

Salvatore Grisanti, MD (Tuebingen, Germany), Olcay Tatar, MD (Tuebingen, Germany), Kei Shinoda, MD, PhD (Tokyo, Japan), Annemarie Adam, (Tuebingen, Germany), Klaus Lucke, MB ChB (Bremen, Germany), Claus Eckardt, MD (Frankfurt, Germany), Peter Stalmans, MD, PhD (Leuven, Belgium), Tillmann Eckert, MD (Frankfurt, Germany), Silvia Bopp, MD (Bremen, Germany), Karl Ulrich Bartz-Schmidt (Tuebingen, Germany) PURPOSE: To evaluate the impact of...

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