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The Effects of Combined Inhibition of Platelet-derived Growth Factor (PDGF-B) and VEGF-A Signaling in Murine Models of Ocular Neovascularization

http://www.evrs.eu/medias/2006/congress/The-Effects-of-Combined-Inhibition-of-Platelet-derived-Growth- Factor-(PDGF-B)-and-VEGF-A-Signaling-in-Murine-Models-of-Ocular-Neovascularization.swf Anthony P. Adamis, MD (New York, NY),* David R. Guyer, MD (New York, NY)* PURPOSE: While the inhibition of VEGF-A signaling can prevent new blood vessel growth in cancer and ocular pathologies, more mature vessels appear to be less susceptible. Since...

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Optical Coherence Tomography Following Pegaptanib Therapy in Diabetics: A Bioanatomic Study of DME

http://www.evrs.eu/medias/2006/congress/Optical-Coherence-Tomography-Following-Pegaptanib-Therapy-in-Diabetics:-A-Bioanatomic-Study-of-DME.swf Mauro Goldbaum, MD (New York, NY),* David R. Guyer, MD (New York, NY),* Barrett Katz,MD (New York, NY)* PURPOSE: Preclincal and clinical data support a role for vascular endothelial growth factor (VEGF)165 in the pathogenesis of ocular neovascular diseases, suggesting that inhibiting the effects of...

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