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Comparision of Wound Leakage Between Straight and Tunnel Scleral Incisions after 25 Gauge Vitrectomy

Luiz F. Hagemann, MD (Blumenau, Brazil),* Luiz Eduardo de A. Marques, MD (Irvine, CA), Baruch D. Kuppermann, MD, PhD (Irvine, CA)* PURPOSE: To compare wound leakage between tunnel and straight scleral incisions after 25 gauge vitrectomy under progressive intraocular pressure elevation testing. METHODS: Ten enucleated New Zealand White rabbit eyes were used. Vitrectomy was performed using the Accurus®/Alcon 25 gauge system. An infusion...

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Response of Different Patterns of Diabetic Macular Edema to Treatment with a Sustained-release Dexamethasone Posterior-segment Drugdelivery System

Baruch D. Kuppermann, MD, PhD (Irvine, CA),* Connie Chou, PhD (Irvine, CA),* David V. Weinberg, MD (Milwaukee, WI),* Scott M. Whitcup, MD (Irvine, CA),* Julia A. Haller, MD (Baltimore, MD),* Mark S. Blumenkranz, MD (Stanford, CA),* George A. Williams, MD (Royal Oak, MI)* PURPOSE: To evaluate the response of different patterns of persistent diabetic macular edema (DME) unresponsive to prior medical or laser therapy to treatment with a novel...

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25-gauge Vitrectomy (from the Outside…)

Luiz Eduardo de Aguiar Marques, MD (Irvine, CA), Faisal Jehan, MD (Irvine, CA), Bogdan Alexandrescu, MD (Irvine, CA), Baruch D. Kuppermann, MD, PhD (Irvine, CA)* SYNOPSIS We show 25-gauge surgeries with an emphasis on external aspects and our technique of tunnelled incisions. We also demonstrate situations that may occur during surgery (cannulas coming out, suturing…). Internal limiting peeling in a diabetic patient, aqueous...

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Safety Profile of Various Steroids on Retinal Cells in Vitro

Baruch D. Kuppermann, MD, PhD (Irvine, CA), Raja Narayanan, MD (Irvine, CA), Saurabh Luthra, MD (Irvine, CA), L. E. Marques, MD (Irvine, CA), Aneesh Neekhra, MD (Irvine, CA), Maria C. Kenney, MD (Irvine, CA) PURPOSE: To study the toxicity of the steroids triamcinolone acetonide (Kenalog®), preservative free triamcinolone (PFTA), dexamethasone, betamethasone, and methyl prednisolone acetate (Depomedrol®) on retinal pigment epithelial...

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