To analyze the changes of the vascular network of the superficial and deep vascular plexus in eyes with symptomatic epiretinal membranes (ERM) and distortion of the parafoveolar retina using the Angiography Module of the Spectralis OCT (Heidelberg Engineering).


The data of the Angio-OCT scans (3 to 3 mm) of four eyes with symptomatic ERM and the four contralateral control eyes were manually segmented as automated layer recognition failed. Subsequently the Spectralis software generated the en-face pictures of the superficial and deep vascular plexus. The resulting OCT-Angiography pictures were then transferred to ImageJ (NIH; Bethesda) for analysis. The avascular area of the superior vascular plexus (FAZA) and the avascular area of the deep vascular plexus (dFAZA) were measured. The superficial retinal vascular density (SRVD) and the deep retinal vascular density (DRVD) were measured. The symmetry vascular density was calculated (nasal-temporal, superior-inferior).


The FAZA and the dFAZA in the eyes with ERM were 0,72±0,48mm2 and 0,81±0,34mm2 in contrast to 0,24±0,10mm2 and 0,27±0,12mm2 in the contralateral eyes, respectively. In the ERM eyes the SRVD and the DRVD were 32,4% and 8%, versus 54,48% and 15,4% in the control eyes, respectively. The distribution of the vascular density was more asymmetric in the ERM eyes.


Additional to the distortion of the retinal surface, the intraretinal vessels are equally affected by symptomatic ERM. Rarefication and disturbance of the vascular pattern can be observed in the superficial and deep vascular plexus by angio OCT.


Burkhard von Jagow
Email : burkhardvjagow@gmail.com
Cell Phone: +491776336968
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