Naomi S. Falk, MD (Albany, NY), Paul M. Beer, MD (Albany, NY), Amjad M. Hammad, MD (Albany, NY)


To explore contrast between objective improvement and visual function.


Study design is a case report of a 55 year old woman who received 2 injections of intravitreal Bevacizumab for Adult Vitelliform dystrophy due to complaints of blurred vision and distortion. She had received 4 prior injections of Pegaptanib sodium without clinical change.


Complete resolution of vitelliform material by OCT, fundus photography and fluorescein angiography but surprising decrease in visual acuity from 20/50 to 20/200.


Rapid absorption of vitelliform material brought on by intravitreal Bevacizumab may cause hastened progression to atrophic stage of vitelliform dystrophy with concurrent visual loss.