Andrij M.Sergienko*, E. Leus, D. Chichur. Eye Microsurgery Center, Kijv, Ukraine.

Purpose:

To evaluate the consequence of acidity intraocular fluids in pathogenesis of proliferative vitreoretinopathy.

Methods:

In a study 210 eyes with retinal detachment and PVR underwent operative treatment. In operative theatre subretinal fluid and vitreus body and blood taking up and measuring of pH were performed.

Results:

Diapason of consequence pH were from 6.7 to 7.5 in vitreus body and from 7.2 to 10.0 in subretinal fluid. Alcalosis of subretinal fluid was in most cases more that in blood. The difference of H+ concentration was observed in cases of acute Retinal detachment * 0.7 -1.4, there were no significant difference in acidity between subretinal fluid and vitreus body in patients with severe PVR.

Conclusions:

In the progress development of retinal detachment and PVR acid-base balance have fase. Deep metabolically alkalosis of subretinal fluid is the cause of it high viscosity and accumulation of plasma proteins in subretinal space. Perhaps the differences in ions concentration between neuroepitelium in posterior eye pole play a role in cells migration and proliferation.