OCT has a peculiar role in guiding in diagnosis and management of peripheral retinal and choroidal lesions

1. Peripheral Retinoschisis: the differential diagnosis between retinoschisis and retinal detachment on retinoschisis is not easy and OCT is very helpful in understanding the nature of the lesion. Retinal detachment maybe a complication of retinoschisis and OCT helps in the identification of retinal detachment in a non-clinically relevant and chronic stage.

2. Peripheral retinal detachment after surgery: OCT helps in the identification of subretinal fluid still present after surgery and its behaviour during the post-operative days

3. Progression of peripheral PVR: peripheral PVR may remain stable or progress toward retinal detachment. OCT helps in understanding the retinal and epiretinal modification during follow up

4. Peripheral pigmented lesions: fluorescein angiography is not consistently able to recognize subretinal fluid on a pigmented lesion. US can give useful information, however OCT is the most reliable exam in detecting subretinal fluid on pigmented lesions.

5. Differentiation of retinitis from retinochoroiditis: Only OCT can help us to understand at which level the lesion is and to better differentiate or confirm the nature of the lesion

6. Diabetic proliferative diabetic retinopathy. In the presence of unclear media, we appreciate peripheral leakage at fluorescein angiography. However, we may not determine with certainty whether it is just vascular leakage or neovascular proliferation. OCT scans on the lesions leads to understand the nature of the leakage

7. Peripheral heterodystrophic disorders affecting the epr and the retina: OCT helps in the assessment of the level of the lesion and guide in the differential diagnosis


Peripheral OCT may be performed by asking the patient to have an extreme gaze in the direction needed. Head may be tilted when needed. Standard vertical or horizontal line scan OCT may be used.


Peripheral OCT is useful to complete the correct diagnosis, and to manage the patients through the follow up.