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Baseline Characteristics

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CSCR-Study-1

 

We collected 1,845 cases of CSCR, sent by 63 retina specialists from 24 countries.

We collected 1,845 cases of CSCR, sent by 63 retina specialists from 24 countries.

This is the geographic distribution of the participant countries with the number of eyes.

This is the geographic distribution of the participant countries with the number of eyes.

 

Here you can see the country distribution and numerosity of cases per country (771 cases came from Turkey, South Corea and Germany) than Poland and Italy account for more than 50% of cases so we have Asia and Europe mainly represented.

Here you can see the country distribution and numerosity of cases per country (771 cases came from Turkey, South Corea and Germany) than Poland and Italy account for more than 50% of cases so we have Asia and Europe mainly represented.

As expected the majority of the patients were male with a prevalence of 77%. The average age of male patients was 46. Females were slightly younger with average age of 40. You may notice that the average age is wide from 20 to 83 years. This could open the discussion between problems with differential diagnosis with AMD and late onset CSCR of just residues of CSCR in old patients who had CSCR at a younger age.

As expected the majority of the patients were male with a prevalence of 77%. The average age of male patients was 46.Females were slightly younger with average age of 40.You may notice that the average age is wide from 20 to 83 years. This could open the discussion between problems with differential diagnosis with AMD and late onset CSCR of just residues of CSCR in old patients who had CSCR at a younger age.

57% of doctors could not refer on concomitant disorders present. Maybe we, as ophthalmologist are not used to ask. Maybe patients did not know. Or maybe most of the patients just did not have any concomitant disorder, which is expected. CSCR is a disease that is known to occur to patients in good health mainly. Among the 26% of patient for whom we have information, hypertension was reported in more than 70%. In Europe the prevalence of hypertension is 35-45% and in South Corea is 25%.

57% of doctors could not refer on concomitant disorders present. Maybe we, as ophthalmologist are not used to ask. Maybe patients did not know. Or maybe most of the patients just did not have any concomitant disorder, which is expected. CSCR is a disease that is known to occur to patients in good health mainly.Among the 26% of patient for whom we have information, hypertension was reported in more than 70%.In Europe the prevalence of hypertension is 35-45% and in South Corea is 25%.

The main known precipitating factor was stressed personality as expected. In fact if we remove the unknown cases it covers almost every reported case.

The main known precipitating factor was stressed personality as expected.In fact if we remove the unknown cases it covers almost every reported case.

Although steroid is known to be one of the risk factors, in this series of CSCR cases, the vast majority had not used steroid in the previous 6 months.

Although steroid is known to be one of the risk factors, in this series of CSCR cases, the vast majority had not used steroid in the previous 6 months.

The estimated duration of the disease at presentation to the doctor was mainly less than 3 months.

The estimated duration of the disease at presentation to the doctor was mainly less than 3 months.

Most of the eyes were emmetrope and 26% hyperope.

Most of the eyes were emmetrope and 26% hyperope.

As we know diagnosis can be made just with OCT. However more than 80% used fluorescein angiography. Too bad we did not ask about indocianine green here.

As we know diagnosis can be made just with OCT. However more than 80% used fluorescein angiography.Too bad we did not ask about indocianine green here.

The reported cases were mostly confined within the arcades

The reported cases were mostly confined within the arcades

and limited to 1 or 2 spot visibles at fluorescein angiography.

and limited to 1 or 2 spot visibles at fluorescein angiography.

Only about 10% of cases were simultaneously bilateral.

Only about 10% of cases were simultaneously bilateral.

Only 30% reported on other findings and among them there were some CNV. This arises the problem of differential diagnosis with AMD in some cases. Were these CNVs simultaneous, appeared after previous treatment? Could them be cases of polypoidal ?

Only 30% reported on other findings and among them there were some CNV. This arises the problem of differential diagnosis with AMD in some cases. Were these CNVs simultaneous, appeared after previous treatment?Could them be cases of polypoidal ?

The same is confirmed with OCT.

The same is confirmed with OCT.

Both for females and males it was the first episodes in almost 70% of cases while it was a recurrence for 30% of them.

Both for females and males it was the first episodes in almost 70% of cases while it was a recurrence for 30% of them.

Most recurrences were 2 to 4.

Most recurrences were 2 to 4.

CSCR-Study-19

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